Using PCR amplification, we target short tandem repeats (STRs) that are located on the chromosomes of interest. The copy number of the STR marker is diagnostic of the copy number of the chromosome.

Carigen utilizes multiplexed diagnostic assays that uses these STR markers to detect the three most common viable autosomal trisomies:

Trisomy 21 (Down syndrome),
Trisomy 18 (Edwards syndrome)
Trisomy 13 (Patau syndrome).

Additional markers on the sex chromosomes X and Y detects the most common sex chromosome aneuploidies:

Klinefelter syndrome (47, XXY)
Turner syndrome (monosomy X)

Our flagship screening system detects a total of 20 markers in one assay. Additional markers on specific systems are utilized if required.

This series of tests have been fully validated for in vitro diagnostic use and suitable for both chorionic villus and amniotic fluid analysis.

Testing is currently on available in Jamaica at select locations. Please contact us for more information.

Click here for more details of the test